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multisite-IRGT

This repository implements the methods in “Designing multicenter individually randomized group treatment trials” by Guangyu Tong, Jiaqi Tong, and Fan Li, published in Biometrical Journal (2024). It contains R scripts for the paper's simulations, numerical illustrations, and trial examples, generating the tables and figure listed below.

Repository contents

Script Output
simulation set 1 code.R Table 2 and Web Tables 1–5.
simulation set 2 code.R Table 3.
FIGURE 2 PLOT CODE.R Figure 2.
STPD CODE.R Table 4.
CODA CODE.R Table 5.

In the simulation scripts, each iteration section corresponds to one column of the relevant table.

Citation

Tong G, Tong J, Li F. Designing multicenter individually randomized group treatment trials. Biometrical Journal. 2024;66(1):e2200307. doi:10.1002/bimj.202200307.

First published online on 28 September 2023; included in the January 2024 issue.

About

R code for designing multicenter individually randomized group treatment trials, including sample size calculations, simulations, and examples. Companion to Tong, Tong, and Li (Biometrical Journal, 2024).

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