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@pinellolab

Pinello Lab

Massachusetts General Hospital/Harvard Medical School

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  1. STREAM STREAM Public

    STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of single-cell data

    Jupyter Notebook 184 50

  2. CRISPResso2 CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    Python 353 117

  3. haystack_bio haystack_bio Public

    Haystack: Epigenetic Variability and Transcription Factor Motifs Analysis Pipeline

    HTML 48 11

  4. CRISPR-SURF CRISPR-SURF Public

    Python 19 3

  5. PrimeDesign PrimeDesign Public

    Software tool for the flexible design of pegRNAs and ngRNAs for prime editing!

    Python 31 7

  6. MotifRaptor MotifRaptor Public

    Explore the effect of genetic variants on transcription factor binding sites

    Python 8 3

Repositories

Showing 10 of 69 repositories
  • crisprme-plus Public

    CRISPRme+ — web/data-manager + optimization successor lineage to CRISPRme (machine identity stays 'crisprme', v2.2.0)

    pinellolab/crisprme-plus's past year of commit activity
    Python 1 0 1 3 Updated Sep 11, 2026
  • PerTurbo Public

    Robust and efficient analysis of single-cell perturbation studies

    pinellolab/PerTurbo's past year of commit activity
    Python 16 MIT 2 1 3 Updated Sep 11, 2026
  • pinellolab/CRISPR_Pipeline's past year of commit activity
    Python 16 MIT 12 7 4 Updated Sep 11, 2026
  • DNA-Diffusion Public

    🧬 Generative modeling of regulatory DNA sequences with diffusion probabilistic models 💨

    pinellolab/DNA-Diffusion's past year of commit activity
    Python 488 61 1 5 Updated Sep 11, 2026
  • CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    pinellolab/CRISPResso2's past year of commit activity
    Python 353 117 47 (1 issue needs help) 2 Updated Sep 10, 2026
  • chorus Public

    One interface to nine genomic deep-learning oracles — variant effect prediction, calibrated per-track percentiles, and plain-English analysis through MCP.

    pinellolab/chorus's past year of commit activity
    Python 63 MIT 11 0 1 Updated Aug 28, 2026
  • CRISPRLungo Public
    pinellolab/CRISPRLungo's past year of commit activity
    Python 12 3 2 0 Updated Aug 26, 2026
  • pinellolab/varaccess-igvf's past year of commit activity
    Python 0 0 0 0 Updated Aug 24, 2026
  • CRISPRme Public

    Variant-aware CRISPR off-target nomination

    pinellolab/CRISPRme's past year of commit activity
    Python 28 10 2 3 Updated Aug 24, 2026
  • CRISPRitz Public

    Tool package to perform in-silico CRISPR analysis and assessment

    pinellolab/CRISPRitz's past year of commit activity
    Python 42 10 1 1 Updated Aug 14, 2026