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SwatiBio/README.md

Hi there 👋

I'm Swati

whoami

Biotech Postgraduate
Bioinformatics Researcher

Interested in
🧬 Multi-Omics Integration (MOFA2, TCGA)
🔬 SLiM Motif Discovery (MEME Suite)
📊 Survival Analysis & Data Science
🛠 Building Reproducible Bioinformatics Pipelines
📚 Learning Advanced Statistical Genomics

🧰 Tech Stack

Languages

Python R Bash

Bioinformatics & Data

Biopython Pandas NumPy Matplotlib SciPy scikit-learn Bioconductor Jupyter

Sequence & Motif Analysis

MEME Suite NCBI BLAST

Tools & Platforms

Git VS Code RStudio

🚀 Featured Projects

Autism SLiM Discovery

Systematic discovery of conserved short linear motifs in intrinsically disordered regions of autism risk genes (SFARI) vs matched controls. MEME discriminative motif discovery, TOMTOM validation, bootstrap analysis, and interactive HTML report.

Python BioPython MEME Suite IUPred3 Fisher's exact test

TCGA-BRCA Multi-Omics MOFA2

Integrating RNA-seq, DNA methylation, and RPPA proteomics from TCGA-BRCA (n=636) using MOFA2. Discovered 15 latent factors linked to breast cancer survival with Cox, RSF, TimeROC, and RMST validation. Interactive Shiny dashboard.

R MOFA2 UCSC Xena Survival Analysis Shiny

📊 GitHub Stats

Swati's GitHub stats

Popular repositories Loading

  1. SwatiBio SwatiBio Public

  2. M.Sc.-thesis M.Sc.-thesis Public

    Genome-wide computational analysis of decanucleotide sequences with a central CG in Human chromosomes 1 and 21 to investigate the influence of flanking sequences on CG methylation.

  3. TCGA-BRCA-Multi-Omics-Project TCGA-BRCA-Multi-Omics-Project Public

    Multi-omics breast cancer analysis covering MOFA2 factor discovery, survival analysis and interactive Shiny dashboard

    R

  4. Autism-SLiM-Discovery Autism-SLiM-Discovery Public

    Systematic discovery of conserved SLiMs in IDRs of autism risk genes (SFARI) vs matched controls

    HTML