diff --git a/rope/base/codeanalyze.py b/rope/base/codeanalyze.py
index d8b8da086..6f2e35d2b 100644
--- a/rope/base/codeanalyze.py
+++ b/rope/base/codeanalyze.py
@@ -524,7 +524,7 @@ def get_formatted_string_pattern():
 
 
 def get_any_string_pattern():
-    prefix = r"[bBfFrRuU]{,4}"
+    prefix = r"[bBfFrRuUtT]{,4}"
     return get_string_pattern_with_prefix(
         prefix,
         prefix_group_name="prefix",
diff --git a/rope/base/simplify.py b/rope/base/simplify.py
index 3198c26de..45f5f0d81 100644
--- a/rope/base/simplify.py
+++ b/rope/base/simplify.py
@@ -26,7 +26,10 @@ def real_code(source):
     for start, end, matchgroups in ignored_regions(source):
         if source[start] == "#":
             replacement = " " * (end - start)
-        elif "f" in matchgroups.get("prefix", "").lower():
+        elif any(
+            prefix in matchgroups.get("prefix", "").lower()
+            for prefix in ("f", "t")
+        ):
             replacement = None
         else:
             replacement = '"%s"' % (" " * (end - start - 2))
diff --git a/ropetest/refactor/renametest.py b/ropetest/refactor/renametest.py
index 9303fb15b..96a71a21a 100644
--- a/ropetest/refactor/renametest.py
+++ b/ropetest/refactor/renametest.py
@@ -319,6 +319,12 @@ def test_renaming_occurrence_in_f_string(self):
         refactored = self._local_rename(code, 2, "new_var")
         self.assertEqual(expected, refactored)
 
+    def test_renaming_occurrence_in_t_string(self):
+        code = 'a = 20\na_string = f(t"{a}(", ")")\n'
+        expected = 'new_var = 20\na_string = f(t"{new_var}(", ")")\n'
+        refactored = self._local_rename(code, 0, "new_var")
+        self.assertEqual(expected, refactored)
+
     def test_renaming_occurrence_in_nested_f_string(self):
         code = dedent("""\
             a_var = 20