diff --git a/packages/sqlite_async/CHANGELOG.md b/packages/sqlite_async/CHANGELOG.md
index c00af79..9d294d4 100644
--- a/packages/sqlite_async/CHANGELOG.md
+++ b/packages/sqlite_async/CHANGELOG.md
@@ -3,6 +3,7 @@
 - Native: Add the `NativeSqliteOpenFactory.beforeOpen` method, which can be overridden to configure
   SQLite asynchronously before opening databases.
 - Web: Upgrade `package:sqlite3_web` to flush IndexedDB writes automatically, deprecate `flush()`.
+- Add `SqliteOptions.preparedStatementCacheSize` to cache prepared statements (disabled by default).
 
 ## 0.14.3
 
diff --git a/packages/sqlite_async/lib/src/native/database/native_sqlite_database.dart b/packages/sqlite_async/lib/src/native/database/native_sqlite_database.dart
index e3c1202..ea6f14d 100644
--- a/packages/sqlite_async/lib/src/native/database/native_sqlite_database.dart
+++ b/packages/sqlite_async/lib/src/native/database/native_sqlite_database.dart
@@ -272,7 +272,8 @@ final class NativeSqliteDatabaseImpl extends SqliteDatabaseImpl {
           [
             for (var i = 0; i < maxReaders; i++) openConnection(isWriter: false)
           ],
-          // TODO: Option to enable prepared statement cache.
+          preparedStatementCacheSize:
+              openFactory.sqliteOptions.preparedStatementCacheSize,
         );
       },
     );
diff --git a/packages/sqlite_async/lib/src/sqlite_options.dart b/packages/sqlite_async/lib/src/sqlite_options.dart
index d722f4e..8785646 100644
--- a/packages/sqlite_async/lib/src/sqlite_options.dart
+++ b/packages/sqlite_async/lib/src/sqlite_options.dart
@@ -1,3 +1,6 @@
+/// @docImport 'package:sqlite3/common.dart';
+library;
+
 final class WebSqliteOptions {
   final String workerUri;
   final String wasmUri;
@@ -43,6 +46,22 @@ final class SqliteOptions {
   /// additional readers on the web.
   final int maxReaders;
 
+  /// The amount of prepared statements to cache.
+  ///
+  /// For each SQLite connection, up to [preparedStatementCacheSize] statements
+  /// will be cached in an LRU cache. This allows re-using prepared statements
+  /// instead of parsing and optimizing them again, which improves performance
+  /// for frequently-used statements like watched queries.
+  ///
+  /// Be aware that active prepared statements may alter the operation of the
+  /// database, for instance because they might keep some database resources
+  /// locked. Statements are [CommonPreparedStatement.reset] before being stored
+  /// in the cache, but enabling a statement cache is still something that
+  /// should be tested carefully.
+  ///
+  /// This is currently disabled by default (set to `0`).
+  final int preparedStatementCacheSize;
+
   @Deprecated('Use default SqliteOptions constructor instead')
   const factory SqliteOptions.defaults() = SqliteOptions;
 
@@ -54,6 +73,7 @@ final class SqliteOptions {
     this.lockTimeout = const Duration(seconds: 30),
     this.profileQueries = _profileQueriesByDefault,
     this.maxReaders = defaultMaxReaders,
+    this.preparedStatementCacheSize = 0,
   });
 
   /// Creates a new options instance by applying overrides from parameters.
@@ -64,6 +84,7 @@ final class SqliteOptions {
     WebSqliteOptions? webSqliteOptions,
     bool? profileQueries,
     int? maxReaders,
+    int? preparedStatementCacheSize,
   }) {
     return SqliteOptions(
       journalMode: journalMode,
@@ -73,6 +94,8 @@ final class SqliteOptions {
       lockTimeout: lockTimeout,
       profileQueries: profileQueries ?? this.profileQueries,
       maxReaders: maxReaders ?? this.maxReaders,
+      preparedStatementCacheSize:
+          preparedStatementCacheSize ?? this.preparedStatementCacheSize,
     );
   }
 
diff --git a/packages/sqlite_async/lib/src/web/web_sqlite_open_factory.dart b/packages/sqlite_async/lib/src/web/web_sqlite_open_factory.dart
index bcd6592..eaf875c 100644
--- a/packages/sqlite_async/lib/src/web/web_sqlite_open_factory.dart
+++ b/packages/sqlite_async/lib/src/web/web_sqlite_open_factory.dart
@@ -64,7 +64,8 @@ base class WebSqliteOpenFactory extends InternalOpenFactory {
   /// can customize the behavior where needed.
   Future<ConnectToRecommendedResult> connectToWorker(
       WebSqlite sqlite, String name) {
-    return sqlite.connectToRecommended(name);
+    return sqlite.connectToRecommended(name,
+        preparedStatementCacheSize: sqliteOptions.preparedStatementCacheSize);
   }
 
   /// Currently this only uses the SQLite Web WASM implementation.
diff --git a/packages/sqlite_async/pubspec.yaml b/packages/sqlite_async/pubspec.yaml
index d43e9c6..eaa54a1 100644
--- a/packages/sqlite_async/pubspec.yaml
+++ b/packages/sqlite_async/pubspec.yaml
@@ -15,7 +15,7 @@ topics:
 dependencies:
   sqlite3: ^3.5.0
   sqlite3_web: ^0.9.4
-  sqlite3_connection_pool: ^0.2.4
+  sqlite3_connection_pool: ^0.2.7
   async: ^2.10.0
   collection: ^1.17.0
   meta: ^1.10.0
diff --git a/packages/sqlite_async/test/utils/abstract_test_utils.dart b/packages/sqlite_async/test/utils/abstract_test_utils.dart
index 29be184..de6dc05 100644
--- a/packages/sqlite_async/test/utils/abstract_test_utils.dart
+++ b/packages/sqlite_async/test/utils/abstract_test_utils.dart
@@ -7,14 +7,14 @@ abstract class AbstractTestUtils {
   Future<CommonDatabase> openDatabaseForSingleConnection();
 
   Future<SqliteOpenFactory> testFactory(
-      {String? path, SqliteOptions options = const SqliteOptions()}) async {
+      {String? path, SqliteOptions options = defaultTestOptions}) async {
     return SqliteOpenFactory(path: path ?? dbPath(), options: options);
   }
 
   /// Creates a SqliteDatabaseConnection
   Future<SqliteDatabase> setupDatabase({
     String? path,
-    SqliteOptions options = const SqliteOptions(),
+    SqliteOptions options = defaultTestOptions,
   }) async {
     final factory = await testFactory(path: path, options: options);
     return SqliteDatabase.withFactory(factory);
@@ -22,4 +22,9 @@ abstract class AbstractTestUtils {
 
   /// Deletes any DB data
   Future<void> cleanDb({required String path});
+
+  // Enable prepared statement cache in tests, we want to enable that option by
+  // default eventually.
+  static const defaultTestOptions =
+      SqliteOptions(preparedStatementCacheSize: 64);
 }
diff --git a/packages/sqlite_async/test/utils/web_test_utils.dart b/packages/sqlite_async/test/utils/web_test_utils.dart
index 34a4469..5542770 100644
--- a/packages/sqlite_async/test/utils/web_test_utils.dart
+++ b/packages/sqlite_async/test/utils/web_test_utils.dart
@@ -57,7 +57,7 @@ class TestUtils extends AbstractTestUtils {
   @override
   Future<SqliteOpenFactory> testFactory({
     String? path,
-    SqliteOptions options = const SqliteOptions(),
+    SqliteOptions options = AbstractTestUtils.defaultTestOptions,
   }) async {
     await _isInitialized;
     return super.testFactory(