diff --git a/c-ext/decompressor.c b/c-ext/decompressor.c
index 97e63742..8defed14 100644
--- a/c-ext/decompressor.c
+++ b/c-ext/decompressor.c
@@ -1684,6 +1684,11 @@ Decompressor_multi_decompress_to_buffer(ZstdDecompressor *self, PyObject *args,
         goto finally;
     }
 
+    if (0 == frameCount) {
+        PyErr_SetString(PyExc_ValueError, "no source elements found");
+        goto finally;
+    }
+
     /* We now have an array with info about our inputs and outputs. Feed it into
        our generic decompression function. */
     frameSources.frames = framePointers;
diff --git a/tests/test_decompressor_multi_decompress_to_buffer.py b/tests/test_decompressor_multi_decompress_to_buffer.py
index eed85fe2..df25ff7c 100644
--- a/tests/test_decompressor_multi_decompress_to_buffer.py
+++ b/tests/test_decompressor_multi_decompress_to_buffer.py
@@ -33,6 +33,21 @@ def test_invalid_inputs(self):
         ):
             dctx.multi_decompress_to_buffer([b"foobarbaz"])
 
+    def test_empty_input(self):
+        dctx = zstd.ZstdDecompressor()
+        frames = [[], zstd.BufferWithSegments(b"", b"")]
+
+        for frame in frames:
+            for threads in (0, 2, -1):
+                for kwargs in ({}, {"decompressed_sizes": b""}):
+                    with self.subTest(
+                        frames=frame, threads=threads, kwargs=kwargs
+                    ):
+                        with self.assertRaises(ValueError):
+                            dctx.multi_decompress_to_buffer(
+                                frame, threads=threads, **kwargs
+                            )
+
     def test_list_input(self):
         cctx = zstd.ZstdCompressor()