diff --git a/packages/core/docs/blocks.md b/packages/core/docs/blocks.md
index fe791da..350a960 100644
--- a/packages/core/docs/blocks.md
+++ b/packages/core/docs/blocks.md
@@ -26,6 +26,11 @@
 
 # Transforms
 
+- `StripMaterialsBlock`
+    - Input: `Document`
+    - Output: `Document`
+    - Uses: glTF Transform document graph
+    - Behavior: Strips materials, assignments, and newly unused textures.
 - `ValidateBlock`
     - Input: `Document`
     - Output: the same `Document`
diff --git a/packages/core/src/blocks/stripMaterialsBlock.ts b/packages/core/src/blocks/stripMaterialsBlock.ts
new file mode 100644
index 0000000..abbfc70
--- /dev/null
+++ b/packages/core/src/blocks/stripMaterialsBlock.ts
@@ -0,0 +1,139 @@
+import { type Document, ExtensionProperty, type Property, Texture, TextureInfo } from "@gltf-transform/core";
+
+import { GltfDocumentType } from "../connectionPoints/gltfDocument";
+import { Block, type BlockOptions } from "./block";
+import { defineBlock } from "./blockDefinition";
+
+const StripMaterialsBlockDefinition = /* @__PURE__ */ defineBlock({
+    type: "transform.strip-materials",
+    input: GltfDocumentType,
+    output: GltfDocumentType,
+    run: stripMaterials,
+});
+
+/** Options for naming the block or supplying its initial input. */
+export type StripMaterialsBlockOptions = BlockOptions<typeof StripMaterialsBlockDefinition>;
+
+/** Strips every authored material, material assignment, and texture made unused by their removal. */
+export class StripMaterialsBlock extends Block<typeof StripMaterialsBlockDefinition> {
+    public constructor(options?: StripMaterialsBlockOptions) {
+        super(StripMaterialsBlockDefinition, options);
+    }
+}
+
+function stripMaterials(document: Document): Document {
+    const root = document.getRoot();
+    const graph = document.getGraph();
+    const materials = root.listMaterials();
+    const materialSet = new Set<Property>(materials);
+    const descendantExtensionProperties = new Set<ExtensionProperty>();
+    const affectedExtensionNames = new Set<string>();
+    const affectedTextureExtensionNames = new Set<string>();
+    const candidateTextures = new Set<Texture>();
+    const pending: Property[] = [...materials];
+    const visited = new Set<Property>();
+    let hasMaterialVariants = false;
+
+    while (pending.length > 0) {
+        const property = pending.pop();
+        if (property === undefined || visited.has(property)) {
+            continue;
+        }
+        visited.add(property);
+
+        for (const edge of graph.listChildEdges(property)) {
+            const child = edge.getChild();
+            if (child instanceof Texture) {
+                candidateTextures.add(child);
+                pending.push(child);
+            } else if (child instanceof ExtensionProperty) {
+                descendantExtensionProperties.add(child);
+                affectedExtensionNames.add(child.extensionName);
+                pending.push(child);
+            } else if (child instanceof TextureInfo) {
+                pending.push(child);
+            }
+        }
+
+        if (materialSet.has(property)) {
+            for (const edge of graph.listParentEdges(property)) {
+                const parent = edge.getParent();
+                if (parent instanceof ExtensionProperty && parent.extensionName === "KHR_materials_variants") {
+                    hasMaterialVariants = true;
+                }
+            }
+        }
+    }
+
+    materials.forEach((material) => material.dispose());
+
+    if (hasMaterialVariants) {
+        root.listExtensionsUsed()
+            .find((extension) => extension.extensionName === "KHR_materials_variants")
+            ?.dispose();
+    }
+
+    let disposedResource = true;
+    while (disposedResource) {
+        disposedResource = disposeOrphanedExtensionProperties(descendantExtensionProperties);
+        for (const texture of candidateTextures) {
+            if (texture.isDisposed()) {
+                candidateTextures.delete(texture);
+            } else if (texture.listParents().every((parent) => parent === root)) {
+                const textureExtensionName = getTextureExtensionName(texture.getMimeType());
+                if (textureExtensionName !== undefined) {
+                    affectedTextureExtensionNames.add(textureExtensionName);
+                }
+                texture.setImage(null).setURI("").setMimeType("").dispose();
+                candidateTextures.delete(texture);
+                disposedResource = true;
+            }
+        }
+    }
+
+    for (const extension of root.listExtensionsUsed()) {
+        const hasNoProperties = affectedExtensionNames.has(extension.extensionName) && extension.listProperties().length === 0;
+        const hasNoTextures = affectedTextureExtensionNames.has(extension.extensionName) && !isTextureExtensionInUse(extension.extensionName, root.listTextures());
+        if (hasNoProperties || hasNoTextures) {
+            extension.dispose();
+        }
+    }
+
+    return document;
+}
+
+function disposeOrphanedExtensionProperties(properties: Set<ExtensionProperty>): boolean {
+    let disposedAnyProperty = false;
+    let disposedProperty = true;
+    while (disposedProperty) {
+        disposedProperty = false;
+        for (const property of properties) {
+            if (property.isDisposed()) {
+                properties.delete(property);
+            } else if (property.listParents().length === 0) {
+                property.dispose();
+                properties.delete(property);
+                disposedProperty = true;
+                disposedAnyProperty = true;
+            }
+        }
+    }
+    return disposedAnyProperty;
+}
+
+function getTextureExtensionName(mimeType: string): string | undefined {
+    switch (mimeType) {
+        case "image/avif":
+            return "EXT_texture_avif";
+        case "image/ktx2":
+            return "KHR_texture_basisu";
+        case "image/webp":
+            return "EXT_texture_webp";
+        default:
+            return undefined;
+    }
+}
+
+function isTextureExtensionInUse(extensionName: string, textures: readonly Texture[]): boolean {
+    return textures.some((texture) => getTextureExtensionName(texture.getMimeType()) === extensionName);
+}
diff --git a/packages/core/src/index.ts b/packages/core/src/index.ts
index 17d3e8a..7c1257c 100644
--- a/packages/core/src/index.ts
+++ b/packages/core/src/index.ts
@@ -1,3 +1,4 @@
+export { StripMaterialsBlock, type StripMaterialsBlockOptions } from "./blocks/stripMaterialsBlock";
 export { EncodeDracoBlock } from "./blocks/encodeDracoBlock";
 export { EncodeKTX2Block } from "./blocks/encodeKtx2Block";
 export { EncodeMeshoptBlock } from "./blocks/encodeMeshoptBlock";
diff --git a/tests/helpers/glb.ts b/tests/helpers/glb.ts
index 96556ff..7714afa 100644
--- a/tests/helpers/glb.ts
+++ b/tests/helpers/glb.ts
@@ -8,6 +8,7 @@ export interface GlbJson {
         readonly byteOffset?: number;
         readonly extensions?: Readonly<Record<string, unknown>>;
     }>;
+    readonly extensions?: Readonly<Record<string, unknown>>;
     readonly extensionsRequired?: readonly string[];
     readonly extensionsUsed?: readonly string[];
     readonly images?: ReadonlyArray<{ readonly bufferView?: number; readonly mimeType?: string; readonly name?: string }>;
@@ -27,7 +28,9 @@ export interface GlbJson {
     }>;
     readonly meshes?: ReadonlyArray<{
         readonly primitives: ReadonlyArray<{
+            readonly attributes?: Readonly<Record<string, number>>;
             readonly extensions?: Readonly<Record<string, unknown>>;
+            readonly material?: number;
         }>;
     }>;
 }
diff --git a/tests/integration/stripMaterials.test.ts b/tests/integration/stripMaterials.test.ts
new file mode 100644
index 0000000..e526990
--- /dev/null
+++ b/tests/integration/stripMaterials.test.ts
@@ -0,0 +1,97 @@
+import { describe, expect, it, vi } from "vitest";
+
+import { GltfInputBlock, GltfOutputBlock, NodeAsset, StripMaterialsBlock } from "../../packages/core/src/index";
+import { parseGlbAsync } from "../helpers/glb";
+import { generateGltfJson, generateTexturedGltfJson } from "../helpers/gltf";
+
+describe("material stripping", () => {
+    it("removes materials, assignments, and newly unused texture data from connected glTF output", async () => {
+        const url = "https://example.com/model.gltf";
+        vi.stubGlobal(
+            "fetch",
+            vi.fn(() => Promise.resolve(new Response(generateExtendedMaterialGltfJson())))
+        );
+
+        try {
+            const source = new GltfInputBlock({ input: url });
+            const stripMaterials = new StripMaterialsBlock();
+            const destination = new GltfOutputBlock();
+            source.output.connectTo(stripMaterials.input);
+            stripMaterials.output.connectTo(destination.input);
+
+            const parsed = await parseGlbAsync(await new NodeAsset({ name: "material-free-glb", outputBlock: destination }).executeAsync());
+            const primitive = parsed.json.meshes?.[0]?.primitives[0];
+
+            expect(parsed.json.materials).toBeUndefined();
+            expect(parsed.json.textures).toBeUndefined();
+            expect(parsed.json.images).toBeUndefined();
+            expect(parsed.json.extensionsUsed ?? []).not.toContain("KHR_materials_clearcoat");
+            expect(parsed.json.extensionsUsed ?? []).not.toContain("KHR_materials_variants");
+            expect(parsed.json.extensionsUsed ?? []).not.toContain("KHR_texture_transform");
+            expect(parsed.json.extensions?.KHR_materials_variants).toBeUndefined();
+            expect(primitive?.material).toBeUndefined();
+            expect(primitive?.extensions?.KHR_materials_variants).toBeUndefined();
+            expect(primitive?.attributes).toEqual({ NORMAL: 1, POSITION: 0, TEXCOORD_0: 2 });
+        } finally {
+            vi.unstubAllGlobals();
+        }
+    });
+
+    it("round trips material-free input without changing geometry", async () => {
+        const url = "https://example.com/model.gltf";
+        vi.stubGlobal(
+            "fetch",
+            vi.fn(() => Promise.resolve(new Response(generateGltfJson())))
+        );
+
+        try {
+            const source = new GltfInputBlock({ input: url });
+            const stripMaterials = new StripMaterialsBlock();
+            const destination = new GltfOutputBlock();
+            source.output.connectTo(stripMaterials.input);
+            stripMaterials.output.connectTo(destination.input);
+
+            const parsed = await parseGlbAsync(await new NodeAsset({ name: "already-material-free-glb", outputBlock: destination }).executeAsync());
+
+            expect(parsed.json.materials).toBeUndefined();
+            expect(parsed.json.meshes?.[0]?.primitives[0]?.attributes).toEqual({ NORMAL: 1, POSITION: 0 });
+        } finally {
+            vi.unstubAllGlobals();
+        }
+    });
+});
+
+function generateExtendedMaterialGltfJson(): string {
+    const gltf = JSON.parse(generateTexturedGltfJson()) as {
+        extensions?: Record<string, unknown>;
+        extensionsUsed?: string[];
+        materials: Array<{ extensions?: Record<string, unknown> }>;
+        meshes: Array<{ primitives: Array<{ extensions?: Record<string, unknown> }> }>;
+    };
+
+    gltf.extensionsUsed = ["KHR_materials_clearcoat", "KHR_materials_variants", "KHR_texture_transform"];
+    gltf.extensions = {
+        KHR_materials_variants: {
+            variants: [{ name: "Alternate" }],
+        },
+    };
+    gltf.materials[0]!.extensions = {
+        KHR_materials_clearcoat: {
+            clearcoatFactor: 1,
+            clearcoatTexture: {
+                index: 0,
+                extensions: {
+                    KHR_texture_transform: {
+                        offset: [0.5, 0.5],
+                    },
+                },
+            },
+        },
+    };
+    gltf.meshes[0]!.primitives[0]!.extensions = {
+        KHR_materials_variants: {
+            mappings: [{ material: 0, variants: [0] }],
+        },
+    };
+    return JSON.stringify(gltf);
+}
diff --git a/tests/unit/stripMaterialsBlock.test.ts b/tests/unit/stripMaterialsBlock.test.ts
new file mode 100644
index 0000000..e9871f5
--- /dev/null
+++ b/tests/unit/stripMaterialsBlock.test.ts
@@ -0,0 +1,125 @@
+import { Document } from "@gltf-transform/core";
+import { EXTMeshFeatures, KHRMaterialsClearcoat, KHRMaterialsVariants, KHRTextureBasisu, KHRTextureTransform, KHRXMP } from "@gltf-transform/extensions";
+import { describe, expect, it } from "vitest";
+
+import { NodeAsset, StripMaterialsBlock } from "../../packages/core/src/index";
+
+describe("StripMaterialsBlock", () => {
+    it("removes every material and only textures made unused by their deletion", async () => {
+        const { document, primitive } = createDocument();
+        const removedTexture = document.createTexture("removed");
+        const preexistingUnusedTexture = document.createTexture("preexisting-unused");
+        const firstMaterial = document.createMaterial("first").setBaseColorTexture(removedTexture);
+        document.createMaterial("second").setEmissiveTexture(removedTexture);
+        primitive.setMaterial(firstMaterial);
+
+        const position = primitive.getAttribute("POSITION");
+        const texCoord = primitive.getAttribute("TEXCOORD_0");
+        const color = primitive.getAttribute("COLOR_0");
+        const indices = primitive.getIndices();
+        const block = new StripMaterialsBlock({ input: document });
+
+        const result = await new NodeAsset({ name: "strip-materials", outputBlock: block }).executeAsync();
+
+        expect(result).toBe(document);
+        expect(document.getRoot().listMaterials()).toEqual([]);
+        expect(primitive.getMaterial()).toBeNull();
+        expect(document.getRoot().listTextures()).toEqual([preexistingUnusedTexture]);
+        expect(primitive.getAttribute("POSITION")).toBe(position);
+        expect(primitive.getAttribute("TEXCOORD_0")).toBe(texCoord);
+        expect(primitive.getAttribute("COLOR_0")).toBe(color);
+        expect(primitive.getIndices()).toBe(indices);
+    });
+
+    it("removes material extension resources while preserving surviving texture uses", async () => {
+        const { document, node, primitive } = createDocument();
+        const sharedTexture = document.createTexture("shared");
+        const extensionTexture = document
+            .createTexture("clearcoat")
+            .setImage(new Uint8Array([1, 2, 3]))
+            .setMimeType("image/ktx2");
+        const material = document.createMaterial("material").setBaseColorTexture(sharedTexture);
+        primitive.setMaterial(material);
+
+        document.createExtension(KHRTextureBasisu).setRequired(true);
+        const clearcoatExtension = document.createExtension(KHRMaterialsClearcoat);
+        const clearcoat = clearcoatExtension.createClearcoat().setClearcoatTexture(extensionTexture);
+        material.setExtension(KHRMaterialsClearcoat.EXTENSION_NAME, clearcoat);
+        const clearcoatTextureInfo = clearcoat.getClearcoatTextureInfo()!;
+        const textureTransformExtension = document.createExtension(KHRTextureTransform);
+        clearcoatTextureInfo.setExtension(KHRTextureTransform.EXTENSION_NAME, textureTransformExtension.createTransform().setOffset([0.5, 0.5]));
+
+        const variantsExtension = document.createExtension(KHRMaterialsVariants);
+        const variant = variantsExtension.createVariant("variant");
+        const mapping = variantsExtension.createMapping().setMaterial(material).addVariant(variant);
+        primitive.setExtension(KHRMaterialsVariants.EXTENSION_NAME, variantsExtension.createMappingList().addMapping(mapping));
+
+        const meshFeaturesExtension = document.createExtension(EXTMeshFeatures);
+        const featureTexture = meshFeaturesExtension.createFeatureIDTexture().setTexture(sharedTexture);
+        const featureId = meshFeaturesExtension.createFeatureID().setFeatureCount(1).setTexture(featureTexture);
+        primitive.setExtension(EXTMeshFeatures.EXTENSION_NAME, meshFeaturesExtension.createFeatures().addFeatureID(featureId));
+
+        const xmpExtension = document.createExtension(KHRXMP);
+        const packet = xmpExtension.createPacket();
+        const texturePacket = xmpExtension.createPacket();
+        material.setExtension(KHRXMP.EXTENSION_NAME, packet);
+        node.setExtension(KHRXMP.EXTENSION_NAME, packet);
+        extensionTexture.setExtension(KHRXMP.EXTENSION_NAME, texturePacket);
+
+        const block = new StripMaterialsBlock({ input: document });
+        await new NodeAsset({ name: "strip-material-extensions", outputBlock: block }).executeAsync();
+
+        expect(document.getRoot().listTextures()).toEqual([sharedTexture]);
+        expect(extensionTexture.getImage()).toBeNull();
+        expect(primitive.getExtension(KHRMaterialsVariants.EXTENSION_NAME)).toBeNull();
+        expect(primitive.getExtension(EXTMeshFeatures.EXTENSION_NAME)).not.toBeNull();
+        expect(node.getExtension(KHRXMP.EXTENSION_NAME)).toBe(packet);
+        expect(xmpExtension.listPackets()).toEqual([packet]);
+        expect(document.getRoot().listExtensionsUsed()).toEqual([meshFeaturesExtension, xmpExtension]);
+        expect(document.getRoot().listExtensionsRequired()).toEqual([]);
+    });
+
+    it("supports material-free documents and repeated execution", async () => {
+        const document = new Document();
+        const preexistingUnusedTexture = document.createTexture("preexisting-unused").setMimeType("image/ktx2");
+        const textureExtension = document.createExtension(KHRTextureBasisu).setRequired(true);
+        const block = new StripMaterialsBlock({ input: document });
+        const asset = new NodeAsset({ name: "strip-no-materials", outputBlock: block });
+
+        await expect(asset.executeAsync()).resolves.toBe(document);
+        await expect(asset.executeAsync()).resolves.toBe(document);
+        expect(document.getRoot().listTextures()).toEqual([preexistingUnusedTexture]);
+        expect(document.getRoot().listExtensionsUsed()).toEqual([textureExtension]);
+        expect(document.getRoot().listExtensionsRequired()).toEqual([textureExtension]);
+    });
+});
+
+function createDocument(): {
+    document: Document;
+    node: ReturnType<Document["createNode"]>;
+    primitive: ReturnType<Document["createPrimitive"]>;
+} {
+    const document = new Document();
+    const buffer = document.createBuffer();
+    const position = document
+        .createAccessor("position", buffer)
+        .setType("VEC3")
+        .setArray(new Float32Array([0, 0, 0, 1, 0, 0, 0, 1, 0]));
+    const texCoord = document
+        .createAccessor("texcoord", buffer)
+        .setType("VEC2")
+        .setArray(new Float32Array([0, 0, 1, 0, 0, 1]));
+    const color = document
+        .createAccessor("color", buffer)
+        .setType("VEC4")
+        .setArray(new Float32Array([1, 0, 0, 1, 0, 1, 0, 1, 0, 0, 1, 1]));
+    const indices = document
+        .createAccessor("indices", buffer)
+        .setType("SCALAR")
+        .setArray(new Uint16Array([0, 1, 2]));
+    const primitive = document.createPrimitive().setAttribute("POSITION", position).setAttribute("TEXCOORD_0", texCoord).setAttribute("COLOR_0", color).setIndices(indices);
+    const mesh = document.createMesh().addPrimitive(primitive);
+    const node = document.createNode().setMesh(mesh);
+    document.createScene().addChild(node);
+    return { document, node, primitive };
+}